Drug Information

Drug General Information
Drug ID
DXR5WF
Drug Name
4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1-carboxylic acid benzylamide
Synonyms
CHEMBL367735
Indication Discovery agent Investigative [1587926]
Formula
C26H27ClN4O
Canonical SMILES
Clc1ccc2C(N3CCN(CC3)C(=O)NCc4ccccc4)c5ncccc5CCc2c1
InChI
InChI=1S/C26H27ClN4O/c27-22-10-11-23-21(17-22)9-8-20-7-4-12-28-24(20)25(23)30-13-15-31(16-14-30)26(32)29-18-19-5-2-1-3-6-19/h1-7,10-12,17,25H,8-9,13-16,18H2,(H,29,32)
InChIKey
XCGOWLIBZVPJPR-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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