Drug Information

Drug General Information
Drug ID
DXRS0M
Drug Name
1-[4-(8-Chloro-5,11-dihydro-10-thia-4-aza-dibenzo[a,d]cyclohepten-5-yl)-piperazin-1-yl]-2-(1-oxy-pyridin-4-yl)-ethanone
Synonyms
CHEMBL423677
Indication Discovery agent Investigative [1587926]
Formula
C24H23ClN4O2S
Canonical SMILES
[O-][n+]1ccc(CC(=O)N2CCN(CC2)C3c4ccc(Cl)cc4SCc5cccnc35)cc1
InChI
InChI=1S/C24H23ClN4O2S/c25-19-3-4-20-21(15-19)32-16-18-2-1-7-26-23(18)24(20)28-12-10-27(11-13-28)22(30)14-17-5-8-29(31)9-6-17/h1-9,15,24H,10-14,16H2
InChIKey
UBHOMARBJHLMPA-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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