Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXS4M5
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| Drug Name |
LESTAURTINIB
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| Synonyms |
SPM-924; CHEMBL603469
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C26H21N3O4
|
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| Canonical SMILES |
C[C@]12O[C@H](C[C@]1(O)CO)n3c4ccccc4c5c6C(=O)NCc6c7c8ccccc8n2c7c35
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| InChI |
InChI=1S/C26H21N3O4/c1-25-26(32,12-30)10-18(33-25)28-16-8-4-2-6-13(16)20-21-15(11-27-24(21)31)19-14-7-3-5-9-17(14)29(25)23(19)22(20)28/h2-9,18,30,32H,10-12H2,1H3,(H,27,31)/t18-,25+,26+/m1/s1
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| InChIKey |
UIARLYUEJFELEN-LROUJFHJSA-N
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| Target and Pathway | |||||
| Target(s) | FL cytokine receptor | Target Info | [1587926] | ||
| Macrophage colony-stimulating factor 1 | Target Info | [1587926] | |||
| KEGG Pathway | Cytokine-cytokine receptor interaction | ||||
| Hematopoietic cell lineage | |||||
| Pathways in cancer | |||||
| Transcriptional misregulation in cancer | |||||
| Acute myeloid leukemia | |||||
| Central carbon metabolism in cancerhsa04014:Ras signaling pathway | |||||
| Rap1 signaling pathway | |||||
| PI3K-Akt signaling pathway | |||||
| Osteoclast differentiation | |||||
| TNF signaling pathway | |||||
| Rheumatoid arthritis | |||||
| Pathway Interaction Database | Signaling events mediated by PTP1B | ||||
| Signaling events mediated by TCPTP | |||||
| Integrins in angiogenesis | |||||
| References | |||||
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