Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXSS1O
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| Drug Name |
Quinoline-8-carboxylic acid{3-methyl-1-[(S)-(S)-3-oxo-1-(pyridine-2-sulfonyl)-azepan-4-ylcarbamoyl]-butyl}-amide
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| Synonyms |
CHEMBL196023
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H31N5O5S
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| Canonical SMILES |
CC(C)C[C@H](NC(=O)c1cccc2cccnc12)C(=O)N[C@H]3CCCN(CC3=O)S(=O)(=O)c4ccccn4
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| InChI |
InChI=1S/C27H31N5O5S/c1-18(2)16-22(31-26(34)20-10-5-8-19-9-6-14-29-25(19)20)27(35)30-21-11-7-15-32(17-23(21)33)38(36,37)24-12-3-4-13-28-24/h3-6,8-10,12-14,18,21-22H,7,11,15-17H2,1-2H3,(H,30,35)(H,31,34)/t21-,22-/m0/s1
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| InChIKey |
OZNGVEHEJAXJKC-VXKWHMMOSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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