Drug Information

Drug General Information
Drug ID
DXTU6Y
Drug Name
(S)-3-Bromo-N-[5-(2-fluoro-phenyl)-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-benzamide
Synonyms
CHEMBL1907851
Indication Discovery agent Investigative [1587926]
Formula
C23H17BrFN3O2
Canonical SMILES
CN1C(=O)[C@@H](NC(=O)c2cccc(Br)c2)N=C(c3ccccc3F)c4ccccc14
InChI
InChI=1S/C23H17BrFN3O2/c1-28-19-12-5-3-10-17(19)20(16-9-2-4-11-18(16)25)26-21(23(28)30)27-22(29)14-7-6-8-15(24)13-14/h2-13,21H,1H3,(H,27,29)/t21-/m1/s1
InChIKey
PSNAHSRRFJSWQU-OAQYLSRUSA-N
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info [1587926]
Cholecystokinin receptor type A Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretionhsa04020:Calcium signaling pathway
Insulin secretion
Pancreatic secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-375276:Peptide ligand-binding receptors
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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