Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXU0E4
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| Drug Name |
7-tert-Butyl-5-[4-(4-methoxy-phenoxy)-phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine
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| Synonyms |
CHEMBL69649
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C23H24N4O2
|
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| Canonical SMILES |
COc1ccc(Oc2ccc(cc2)c3cn(c4ncnc(N)c34)C(C)(C)C)cc1
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| InChI |
InChI=1S/C23H24N4O2/c1-23(2,3)27-13-19(20-21(24)25-14-26-22(20)27)15-5-7-17(8-6-15)29-18-11-9-16(28-4)10-12-18/h5-14H,1-4H3,(H2,24,25,26)
|
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| InChIKey |
NJSMJBCABAFTHE-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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