Drug Information

Drug General Information
Drug ID
DXU1ER
Drug Name
4'-{[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-amino}-[1,1';2',1'']terphenyl-3-carboxylic acid methyl ester 25 (FTI-2297)
Synonyms
FTI-2297; CHEMBL292361
Indication Discovery agent Investigative [1587926]
Formula
C32H26N4O2
Canonical SMILES
COC(=O)c1cccc(c1)c2ccc(NCc3cncn3Cc4ccc(cc4)C#N)cc2c5ccccc5
InChI
InChI=1S/C32H26N4O2/c1-38-32(37)27-9-5-8-26(16-27)30-15-14-28(17-31(30)25-6-3-2-4-7-25)35-20-29-19-34-22-36(29)21-24-12-10-23(18-33)11-13-24/h2-17,19,22,35H,20-21H2,1H3
InChIKey
PWGAFSATAZGSFE-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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