Drug Information

Drug General Information
Drug ID
DXU4UN
Drug Name
(R)-2-Bromo-N-[5-(2-fluoro-phenyl)-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-benzamide
Synonyms
CHEMBL2092866
Indication Discovery agent Investigative [1587926]
Formula
C23H17BrFN3O2
Canonical SMILES
CN1C(=O)[C@H](NC(=O)c2ccccc2Br)N=C(c3ccccc3F)c4ccccc14
InChI
InChI=1S/C23H17BrFN3O2/c1-28-19-13-7-4-10-16(19)20(15-9-3-6-12-18(15)25)26-21(23(28)30)27-22(29)14-8-2-5-11-17(14)24/h2-13,21H,1H3,(H,27,29)/t21-/m0/s1
InChIKey
QOBSCDLYMYAIFX-NRFANRHFSA-N
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info [1587926]
Cholecystokinin receptor type A Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretionhsa04020:Calcium signaling pathway
Insulin secretion
Pancreatic secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-375276:Peptide ligand-binding receptors
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.