Drug Information

Drug General Information
Drug ID
DXU5T6
Drug Name
N-(cyclohexylmethyl)-2-(2,2,2-trifluoroacetyl)thiazole-5-carboxamide
Synonyms
CHEMBL524024
Indication Discovery agent Investigative [1587926]
Formula
C13H15F3N2O2S
Canonical SMILES
FC(F)(F)C(=O)c1ncc(s1)C(=O)NCC2CCCCC2
InChI
InChI=1S/C13H15F3N2O2S/c14-13(15,16)10(19)12-18-7-9(21-12)11(20)17-6-8-4-2-1-3-5-8/h7-8H,1-6H2,(H,17,20)
InChIKey
ZOPFCMCXTRDDOT-UHFFFAOYSA-N
Target and Pathway
Target(s) Histone deacetylase 6 Target Info [1587926]
Histone deacetylase 4 Target Info [1587926]
KEGG Pathway Alcoholism
Viral carcinogenesishsa05034:Alcoholism
Epstein-Barr virus infection
Viral carcinogenesis
MicroRNAs in cancer
NetPath Pathway IL2 Signaling Pathway
Pathway Interaction Database Signaling events mediated by HDAC Class II
Signaling events mediated by HDAC Class Ihdac_classii_pathway:Signaling events mediated by HDAC Class II
Signaling events mediated by HDAC Class III
Signaling events mediated by HDAC Class I
Sumoylation by RanBP2 regulates transcriptional repression
Validated nuclear estrogen receptor alpha network
Reactome NOTCH1 Intracellular Domain Regulates Transcription
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
Assembly of the primary ciliumR-HSA-2122947:NOTCH1 Intracellular Domain Regulates Transcription
WikiPathways Ectoderm Differentiation
Neural Crest Differentiation
Cell CycleWP474:Endochondral Ossification
Cardiac Hypertrophic Response
miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBase
miR-targeted genes in epithelium - TarBase
TarBasePathway
Cell Cycle
MicroRNAs in cardiomyocyte hypertrophy
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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