Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXV0T0
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| Drug Name |
((S)-3-Methyl-1-{2-[4-(1-methyl-piperidin-4-yloxy)-phenylamino]-ethylcarbamoyl}-butyl)-carbamic acid benzyl ester
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| Synonyms |
CHEMBL59277
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H40N4O4
|
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| Canonical SMILES |
CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)NCCNc2ccc(OC3CCN(C)CC3)cc2
|
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| InChI |
InChI=1S/C28H40N4O4/c1-21(2)19-26(31-28(34)35-20-22-7-5-4-6-8-22)27(33)30-16-15-29-23-9-11-24(12-10-23)36-25-13-17-32(3)18-14-25/h4-12,21,25-26,29H,13-20H2,1-3H3,(H,30,33)(H,31,34)/t26-/m0/s1
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| InChIKey |
KSKVIZXIXFRARN-SANMLTNESA-N
|
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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