Drug Information

Drug General Information
Drug ID
DXW02Z
Drug Name
N-{2-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-oxo-ethyl}-2-mercapto-propionamide
Synonyms
CHEMBL445917
Indication Discovery agent Investigative [1587926]
Formula
C23H27ClN4O2S
Canonical SMILES
CC(S)C(=O)NCC(=O)N1CCN(CC1)C2c3ccc(Cl)cc3CCc4cccnc24
InChI
InChI=1S/C23H27ClN4O2S/c1-15(31)23(30)26-14-20(29)27-9-11-28(12-10-27)22-19-7-6-18(24)13-17(19)5-4-16-3-2-8-25-21(16)22/h2-3,6-8,13,15,22,31H,4-5,9-12,14H2,1H3,(H,26,30)
InChIKey
JMSJKAZJFPCPAD-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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