Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXW9TR
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| Drug Name |
N-{(S)-3-Cyclohexyl-1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-propyl}-3-methyl-benzamide
|
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| Synonyms |
CHEMBL198147
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H37N3O3
|
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| Canonical SMILES |
COc1ccc(NCCNC(=O)[C@H](CCC2CCCCC2)NC(=O)c3cccc(C)c3)cc1
|
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| InChI |
InChI=1S/C27H37N3O3/c1-20-7-6-10-22(19-20)26(31)30-25(16-11-21-8-4-3-5-9-21)27(32)29-18-17-28-23-12-14-24(33-2)15-13-23/h6-7,10,12-15,19,21,25,28H,3-5,8-9,11,16-18H2,1-2H3,(H,29,32)(H,30,31)/t25-/m0/s1
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| InChIKey |
MNECACXIBPFIKN-VWLOTQADSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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