Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXX4BL
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| Drug Name |
[(S)-1-((2S,3S)-2-tert-Butoxy-4-oxo-azetidin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester
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| Synonyms |
CHEMBL30957
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H29N3O5
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| Canonical SMILES |
CC(C)(C)O[C@@H]1NC(=O)[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)OCc3ccccc3
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| InChI |
InChI=1S/C24H29N3O5/c1-24(2,3)32-22-19(21(29)27-22)26-20(28)18(14-16-10-6-4-7-11-16)25-23(30)31-15-17-12-8-5-9-13-17/h4-13,18-19,22H,14-15H2,1-3H3,(H,25,30)(H,26,28)(H,27,29)/t18-,19+,22-/m0/s1
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| InChIKey |
RHNULCWVJCENCM-JQVVWYNYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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