Drug Information

Drug General Information
Drug ID
DXXG3S
Drug Name
4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1,2-dicarboxylic acid 1-cyclohexylamide 2-[1,3,4]thiadiazol-2-ylamide
Synonyms
CHEMBL370621
Indication Discovery agent Investigative [1587926]
Formula
C28H31BrClN7O2S
Canonical SMILES
Clc1ccc2C(N3CCN(C(C3)C(=O)Nc4nncs4)C(=O)NC5CCCCC5)c6ncc(Br)cc6CCc2c1
InChI
InChI=1S/C28H31BrClN7O2S/c29-19-12-18-7-6-17-13-20(30)8-9-22(17)25(24(18)31-14-19)36-10-11-37(28(39)33-21-4-2-1-3-5-21)23(15-36)26(38)34-27-35-32-16-40-27/h8-9,12-14,16,21,23,25H,1-7,10-11,15H2,(H,33,39)(H,34,35,38)
InChIKey
JUGYLGCPMTUAIY-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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