Drug Information
| Drug General Information | |||||
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| Drug ID |
DXXG6Y
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| Drug Name |
(2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(4-oxo-3,4-dihydro-quinazoline-6-sulfonylamino)-succinamide
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| Synonyms |
CHEMBL342100
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C23H34N6O7S
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| Canonical SMILES |
CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1ccc2ncnc(O)c2c1)C(=O)NO)C(C)(C)C
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| InChI |
InChI=1S/C23H34N6O7S/c1-12(2)9-15(20(31)27-18(22(33)24-6)23(3,4)5)17(21(32)28-34)29-37(35,36)13-7-8-16-14(10-13)19(30)26-11-25-16/h7-8,10-12,15,17-18,29,34H,9H2,1-6H3,(H,24,33)(H,27,31)(H,28,32)(H,25,26,30)/t15-,17+,18-/m1/s1
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| InChIKey |
GPENKXZRTRUYOG-BPQIPLTHSA-N
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| Target and Pathway | |||||
| Target(s) | Interstitial collagenase | Target Info | [1587926] | ||
| Neutrophil collagenase | Target Info | [1587926] | |||
| WikiPathways | TGF beta Signaling Pathway | ||||
| Bladder Cancer | |||||
| Activation of Matrix Metalloproteinases | |||||
| Degradation of collagen | |||||
| Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis | |||||
| Oncostatin M Signaling Pathway | |||||
| Prostate Cancer | |||||
| Integrated Breast Cancer Pathway | |||||
| Integrated Cancer pathway | |||||
| Cell surface interactions at the vascular wall | |||||
| Matrix MetalloproteinasesWP2769:Activation of Matrix Metalloproteinases | |||||
| Matrix Metalloproteinases | |||||
| References | |||||
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