Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXXN9K
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| Drug Name |
{(S)-1-[(S)-1-Benzyl-2-(biphenyl-4-ylamino)-ethylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester
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| Synonyms |
CHEMBL171998
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C35H39N3O3
|
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| Canonical SMILES |
CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@H](CNc2ccc(cc2)c3ccccc3)Cc4ccccc4
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| InChI |
InChI=1S/C35H39N3O3/c1-26(2)22-33(38-35(40)41-25-28-14-8-4-9-15-28)34(39)37-32(23-27-12-6-3-7-13-27)24-36-31-20-18-30(19-21-31)29-16-10-5-11-17-29/h3-21,26,32-33,36H,22-25H2,1-2H3,(H,37,39)(H,38,40)/t32-,33-/m0/s1
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| InChIKey |
HKUZYWOFHOTSIY-LQJZCPKCSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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