Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXY6YO
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| Drug Name |
(R)-2-(cyclohexylmethyl)-4-morpholino-4-oxo-N-((S)-4-phenyl-1-(4-(trifluoromethoxy)phenylamino)butan-2-yl)butanamide
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| Synonyms |
CHEMBL239580
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C32H42F3N3O4
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| Canonical SMILES |
FC(F)(F)Oc1ccc(NC[C@H](CCc2ccccc2)NC(=O)[C@H](CC3CCCCC3)CC(=O)N4CCOCC4)cc1
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| InChI |
InChI=1S/C32H42F3N3O4/c33-32(34,35)42-29-15-13-27(14-16-29)36-23-28(12-11-24-7-3-1-4-8-24)37-31(40)26(21-25-9-5-2-6-10-25)22-30(39)38-17-19-41-20-18-38/h1,3-4,7-8,13-16,25-26,28,36H,2,5-6,9-12,17-23H2,(H,37,40)/t26-,28+/m1/s1
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| InChIKey |
IRBSFNODBMYMJG-IAPPQJPRSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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