Drug Information

Drug General Information
Drug ID
DXZ8CO
Drug Name
4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-hexanoyl-piperazine-2-caboxylic acid (pyridin-3-ylmethyl)-amide
Synonyms
CHEMBL201043
Indication Discovery agent Investigative [1587926]
Formula
C31H35BrClN5O2
Canonical SMILES
CCCCCC(=O)N1CCN(CC1C(=O)NCc2cccnc2)C3c4ccc(Cl)cc4CCc5cc(Br)cnc35
InChI
InChI=1S/C31H35BrClN5O2/c1-2-3-4-7-28(39)38-14-13-37(20-27(38)31(40)36-18-21-6-5-12-34-17-21)30-26-11-10-25(33)16-22(26)8-9-23-15-24(32)19-35-29(23)30/h5-6,10-12,15-17,19,27,30H,2-4,7-9,13-14,18,20H2,1H3,(H,36,40)
InChIKey
BMAWJYDMAVDMKG-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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