Drug General Information
Drug ID
DXZV8F
Drug Name
N-(3-Dibenzylamino-2-methyl-phenyl)-methanesulfonamide
Synonyms
CHEMBL419633
Indication Discovery agent Investigative [1587926]
Formula
C22H24N2O2S
Canonical SMILES
Cc1c(NS(=O)(=O)C)cccc1N(Cc2ccccc2)Cc3ccccc3
InChI
InChI=1S/C22H24N2O2S/c1-18-21(23-27(2,25)26)14-9-15-22(18)24(16-19-10-5-3-6-11-19)17-20-12-7-4-8-13-20/h3-15,23H,16-17H2,1-2H3
InChIKey
WGGMBWMYJSVPSG-UHFFFAOYSA-N
Target and Pathway
Target(s) Progesterone receptor Target Info [1587926]
mRNA of androgen receptor Target Info [1587926]
KEGG Pathway Oocyte meiosis
Progesterone-mediated oocyte maturationhsa04114:Oocyte meiosis
Pathways in cancer
Prostate cancer
NetPath Pathway EGFR1 Signaling Pathway
AndrogenReceptor Signaling Pathway
FSH Signaling Pathway
Pathway Interaction Database Cellular roles of Anthrax toxinsmad2_3nuclearpathway:Regulation of nuclear SMAD2/3 signaling
Coregulation of Androgen receptor activity
Regulation of Androgen receptor activity
Nongenotropic Androgen signaling
Regulation of nuclear beta catenin signaling and target gene transcription
FOXA1 transcription factor network
Notch-mediated HES/HEY network
Reactome Nuclear signaling by ERBB4
Nuclear Receptor transcription pathwayR-HSA-383280:Nuclear Receptor transcription pathway
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
WikiPathways Ovarian Infertility Genes
Signaling by ERBB4
Nuclear ReceptorsWP706:SIDS Susceptibility Pathways
Integrated Pancreatic Cancer Pathway
Prostate Cancer
Integrated Breast Cancer Pathway
Nuclear Receptors
Androgen receptor signaling pathway
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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