Drug General Information
Drug ID	D00CPM
Former ID	DNC014570
Drug Name	2-(4-Methoxy-phenyl)-1H-indole-3-carbaldehyde
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[534765]
Structure		Download 2D MOL 3D MOL
Formula	C16H13NO2
Canonical SMILES	COC1=CC=C(C=C1)C2=C(C3=CC=CC=C3N2)C=O
InChI	1S/C16H13NO2/c1-19-12-8-6-11(7-9-12)16-14(10-18)13-4-2-3-5-15(13)17-16/h2-10,17H,1H3
InChIKey	QIMWZVMNUAWWSJ-UHFFFAOYSA-N
PubChem Compound ID	3826063
Target and Pathway
Target(s)	Tubulin	Target Info	Inhibitor	[534765]
	Tubulin beta	Target Info	Inhibitor	[534765]
KEGG Pathway	Phagosome
	Gap junction
	Pathogenic Escherichia coli infection
NetPath Pathway	FSH Signaling Pathway
	TCR Signaling Pathway
	EGFR1 Signaling Pathway
PANTHER Pathway	Cytoskeletal regulation by Rho GTPase
	Huntington disease
Reactome	Regulation of PLK1 Activity at G2/M Transition
	Loss of Nlp from mitotic centrosomes
	Recruitment of mitotic centrosome proteins and complexes
	Loss of proteins required for interphase microtubule organization?from the centrosome
	Anchoring of the basal body to the plasma membrane
WikiPathways	Parkin-Ubiquitin Proteasomal System pathway
	Pathogenic Escherichia coli infection
	Mitotic G2-G2/M phases
References
Ref 534765	J Med Chem. 1998 Dec 3;41(25):4965-72.Methoxy-substituted 3-formyl-2-phenylindoles inhibit tubulin polymerization.
Ref 534765	J Med Chem. 1998 Dec 3;41(25):4965-72.Methoxy-substituted 3-formyl-2-phenylindoles inhibit tubulin polymerization.

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