Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D00CSQ
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| Former ID |
DAP001435
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| Drug Name |
Triclosan
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| Synonyms |
Aquasept; Cliniclean; Cloxifenol; Cloxifenolum; Irgasan; Manusept; Sapoderm; TCL; Triclosanum; Trisan; Clearasil DailyFace Wash; Dermtek Brand of Triclosan; GlaxoSmithKline Brand of Triclosan; Microshield T; Oxy Skin Wash; Pharmachem Brand of Triclosan; Reckitt Brand of Triclosan; SSL Brand of Triclosan; Ster Zac Bath Concentrate; SterZac Bath Concentrate; Trans Canaderm Brand of Triclosan; Triclosan Pharmachem Brand; Triclosan Reckitt Brand; CH 3565; IN1424; Irgasan DP 300; Irgasan DP300; Lexol 300; CH-3565; DP-300; Johnson & Johnson Brand of Triclosan; Procter & Gamble Brand of Triclosan; Ster-Zac Bath Concentrate; Stri-Dex Cleansing Bar; Stri-Dex Face Wash; Triclosanum [INN-Latin]; Stri-Dex cleansing bar (TN); Triclosan (USP/INN); Triclosan [USAN:BAN:INN]; Ether, 2'-hydroxy-2,4,4'-trichlorodiphenyl; 2,4,4'-Trichloro-2'-hydroxy diphenyl ether; 2,4,4'-Trichloro-2'-hydroxydiphenyl ether; 2-Hydroxy-2',4,4'-trichlorodiphenyl Ether; 5-CHLORO-2-(2,4-DICHLOROPHENOXY)PHENOL; 5-Chloro-2-(2,4-dichloro-phenoxy)-phenol
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| Drug Type |
Small molecular drug
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| Indication | Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] | Approved | [536463] | ||
| Therapeutic Class |
Antibiotics
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| Structure |
|
Download2D MOL |
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| Formula |
C12H7Cl3O2
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| Canonical SMILES |
C1=CC(=C(C=C1Cl)O)OC2=C(C=C(C=C2)Cl)Cl
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| InChI |
1S/C12H7Cl3O2/c13-7-1-3-11(9(15)5-7)17-12-4-2-8(14)6-10(12)16/h1-6,16H
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| InChIKey |
XEFQLINVKFYRCS-UHFFFAOYSA-N
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| CAS Number |
CAS 3380-34-5
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| PubChem Compound ID | |||||
| PubChem Substance ID |
14214, 584337, 638158, 827598, 830483, 830851, 836967, 5664285, 7890716, 8153420, 10322303, 11109466, 12016155, 14720377, 14922470, 24698180, 24874395, 24886448, 26754498, 26759661, 29215355, 29224604, 47193732, 47207884, 48426058, 49674565, 49832484, 49903859, 49968902, 50109854, 53789200, 53800864, 56313852, 56314344, 57244094, 57260157, 57260158, 57322843, 57389809, 57652433, 79532964, 85172710, 85256706, 87350665, 87577595, 87692612, 91011813, 92308067, 92710097, 99445075
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| SuperDrug ATC ID |
D08AE04; D09AA06
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| SuperDrug CAS ID |
cas=003380345
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| Target and Pathway | |||||
| Target(s) | Enoyl-ACP reductase | Target Info | Binder | [535276], [535329], [536636] | |
| References | |||||
| Ref 535276 | Lipid biosynthesis as a target for antibacterial agents. Prog Lipid Res. 2001 Nov;40(6):467-97. | ||||
| Ref 535329 | The apicoplast as an antimalarial drug target. Drug Resist Updat. 2001 Jun;4(3):145-51. | ||||
| Ref 536636 | Novel molecular targets for antimalarial drug development. Chem Biol Drug Des. 2008 Apr;71(4):287-97. Epub 2008 Feb 22. | ||||
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