Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D00DJX
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| Former ID |
DNC010658
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| Drug Name |
JNJ-17148066
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [530079] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C30H31NO5
|
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| Canonical SMILES |
C1CCN(CC1)CCOC2=CC=C(C=C2)C3C4=C(CCOC5=C4C=CC(=C5)O)C6=<br />C(O3)C=C(C=C6)O
|
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| InChI |
1S/C30H31NO5/c32-21-7-11-26-27(18-21)35-16-12-25-24-10-6-22(33)19-28(24)36-30(29(25)26)20-4-8-23(9-5-20)34-17-15-31-13-2-1-3-14-31/h4-11,18-19,30,32-33H,1-3,12-17H2/t30-/m1/s1
|
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| InChIKey |
OFYZVZJXVRFMIW-SSEXGKCCSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Estrogen receptor | Target Info | Inhibitor | [530079] | |
| Pathway Interaction Database | Regulation of nuclear SMAD2/3 signaling | ||||
| Signaling events mediated by HDAC Class II | |||||
| Plasma membrane estrogen receptor signaling | |||||
| LKB1 signaling events | |||||
| Regulation of Telomerase | |||||
| ATF-2 transcription factor network | |||||
| AP-1 transcription factor network | |||||
| FOXM1 transcription factor network | |||||
| Validated nuclear estrogen receptor alpha network | |||||
| Signaling mediated by p38-alpha and p38-beta | |||||
| FOXA1 transcription factor network | |||||
| References | |||||
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