Drug Information

Drug General Information
Drug ID
D00EEL
Former ID
DAP001385
Drug Name
Gaboxadol
Synonyms
Gaboxadolum; THIP; Gaboxadolum [Latin]; LU 2030; Gaboxadol [USAN:INN]; Lu 02-030; MK-0928; Gaboxadol (USAN/INN); LU-2-030; Lu-02-030; Isoxazolo(5,4-c)pyridin-3(2H)-one, 4,5,6,7-tetrahydro-, hydrate; 4,5,6,7-Tetrahydroisoxazole(5,4-c)pyridin-3-ol; 4,5,6,7-Tetrahydroisoxazolo(5,4-c)pyridin-3-ol; 4,5,6,7-tetrahydro-[1,2]oxazolo[5,4-c]pyridin-3-one
Drug Type
Small molecular drug
Indication Insomnia [ICD9: 307.41, 307.42, 327.0, 780.51, 780.52; ICD10:F51.0, G47.0] Approved [467660], [537521]
Therapeutic Class
Hypnotics and Sedatives
Company
Merck & Co
Structure
Download
2D MOL

3D MOL
Formula
C6H8N2O2
InChI
InChI=1S/C6H8N2O2/c9-6-4-1-2-7-3-5(4)10-8-6/h7H,1-3H2,(H,8,9)
InChIKey
ZXRVKCBLGJOCEE-UHFFFAOYSA-N
CAS Number
CAS 64603-91-4
PubChem Compound ID
3448
PubChem Substance ID
586282, 5651498, 5694188, 7980780, 8152193, 11111836, 11111837, 11113715, 11335386, 11360625, 11364378, 11366940, 11369502, 11371576, 11373822, 11377664, 11461597, 11467000, 11468120, 11485296, 11486650, 11489406, 11490544, 11491987, 11495298, 12015406, 14747760, 15194598, 26751902, 29222582, 47206216, 47211771, 47365059, 47515197, 47588874, 47885286, 47959606, 47959607, 48110332, 48184876, 48259099, 49698969, 49987818, 50104580, 50684001, 57321806, 81065560, 90341079, 103286434, 104121647
Target and Pathway
Target(s) GABA A receptor delta subunit Target Info Modulator
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
References
Ref 467660(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4322).
Ref 537521Highway driving performance and cognitive functioning the morning after bedtime and middle-of-the-night use of gaboxadol, zopiclone and zolpidem. J Sleep Res. 2009 Jun 22.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.