Drug Information

Drug General Information
Drug ID
D00ENY
Former ID
DAP000015
Drug Name
L-Glutamic Acid
Synonyms
Aciglut; Glu; Glusate; Glut; Glutacid; Glutamate; Glutamicol; Glutamidex; Glutaminol; Glutaton; Gulutamine; Acide glutamique; Acido glutamico; Acidum glutamicum; Acidum glutaminicum; GLUTAMIC ACID; Glutamic acid polymer; Glutaminic acid; POLYGLUTAMIC ACID; E 620; A-Aminoglutaric acid; A-Glutamic acid; Acide glutamique [INN-French]; Acido glutamico [INN-Spanish]; Acidum glutamicum [INN-Latin]; Alpha-Glutamic acid; Alpha-aminoglutaric acid; D-Glutamiensuur; Glutamic Acid [USAN:INN]; Glutamic acid (VAN); Glutaminic acid (VAN); Gulutamine (USP); L-Glutamic acid hydrochloride; L-Glutaminic acid; L-Glutaminsaeure; L-glu; L-glutamate; Alpha-Aminoglutaric acid (VAN); Alpha-L-Glutamic acid polymer; Glutamic Acid (L-glutamic acid); Glutamic acid (H-3); H-Glu-OH; L-2-Aminoglutaric acid; L-Glutamic acid (9CI); L-Glutamic acid (JAN); L-Glutamic acid, homopolymer; L-a-Aminoglutaric acid; L-alpha-Aminoglutaric acid; Poly-L-glutamate; Sodium Glutamate (L-glutamic Acid); Glutamic acid, L-, peptides; L-Glutamic acid, homopolymer (9CI); Poly(alpha-L-glutamic acid); Glutamic acid, L-(7CI,8CI); L-(+)-glutamic acid; (2S)-2-Aminopentanedioic acid; (S)-(+)-Glutamic acid; (S)-2-Aminopentanedioic acid; (S)-Glutamic acid; 1-Aminopropane-1,3-dicarboxylic acid; 2-Aminoglutaric acid; 2-aminopentanedioic acid
Drug Type
Small molecular drug
Indication Schizophrenia; Indigestion [ICD9: 295; ICD10:F20, K30] Approved [536838], [538847], [551871]
Therapeutic Class
Dietary supplement
Structure
Download
2D MOL

3D MOL
Formula
C5H9NO4
InChI
InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
InChIKey
WHUUTDBJXJRKMK-VKHMYHEASA-N
CAS Number
CAS 56-86-0
PubChem Compound ID
33032
PubChem Substance ID
3327, 627126, 820094, 820617, 822192, 822517, 822724, 822932, 823119, 825074, 826975, 828108, 841758, 854467, 854468, 854502, 7847075, 7887923, 7979423, 8023666, 8026291, 8026293, 8143737, 8172949, 10527679, 11110117, 11110137, 11113412, 11528393, 11538992, 14710662, 14716143, 14719817, 14719819, 15297417, 16918839, 17404216, 17422134, 17422293, 24846358, 24872908, 24895052, 24895223, 24895340, 24901609, 24902257, 26746616, 26751652, 34674977, 46391925
ChEBI ID
ChEBI:16015
SuperDrug ATC ID
B03BB01
SuperDrug CAS ID
cas=000059303
Target and Pathway
Target(s) NMDA receptor Target Info Antagonist [536888]
References
Ref 536838Emerging drugs for chemotherapy-induced mucositis. Expert Opin Emerg Drugs. 2008 Sep;13(3):511-22.
Ref 538847(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1369).
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 536888Altered expression of genes involved in GABAergic transmission and neuromodulation of granule cell activity in the cerebellum of schizophrenia patients. Am J Psychiatry. 2008 Dec;165(12):1594-603. Epub 2008 Oct 15.

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