Drug General Information
Drug ID
D00GMT
Drug Name
CS-551
Synonyms
CS-551
Drug Type
Small molecular drug
Indication Unspecified Investigative [1560274], [1560340]
Formula
C18H22N4O4
PubChem Compound ID
Target and Pathway
Target(s) Glycoprotein IIb/IIIa receptor Target Info Modulator
Reactome Platelet degranulation
Elastic fibre formation
PECAM1 interactions
Molecules associated with elastic fibres
Integrin cell surface interactions
Syndecan interactions
ECM proteoglycans
Integrin alphaIIb beta3 signaling
GRB2:SOS provides linkage to MAPK signaling for Integrins
p130Cas linkage to MAPK signaling for integrins
VEGFA-VEGFR2 Pathway
MAP2K and MAPK activation
WikiPathways Focal Adhesion
Hematopoietic Stem Cell Differentiation
Human Complement System
Extracellular matrix organization
Arrhythmogenic Right Ventricular Cardiomyopathy
Integrin-mediated Cell Adhesion
L1CAM interactions
Integrin cell surface interactions
Integrin alphaIIb beta3 signaling
References
Ref 1560274Glycoprotein IIb/IIIa receptor number and occupancy during chronic administration of an oral antagonist.
Ref 1560340Acute thrombocytopenia in patients treated with the oral glycoprotein IIb/IIIa inhibitors xemilofiban and orbofiban: evidence for an immune etiology.

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