Drug Information

Drug General Information
Drug ID
D00GNJ
Former ID
DCL000868
Drug Name
Linaclotide
Synonyms
Linaclotide (USAN)
Drug Type
Small molecular drug
Indication Irritable bowel syndrome with constipation; Chronic idiopathic constipation [ICD10:K59] Approved [468128], [536527]
Company
Microbia
Structure
Download
2D MOL

3D MOL
Formula
C59H79N15O21S6
CAS Number
CAS 851199-59-2
PubChem Compound ID
16158208
PubChem Substance ID
17491264, 28748208, 40691235, 96026035, 135264508, 141198379, 160645770, 162224779, 163679254, 175427136, 238116083, 242651865, 247301501, 252218581
SuperDrug ATC ID
A06AX04
Target and Pathway
Target(s) Guanylyl cyclase C Target Info Activator [536527]
References
Ref 468128(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5017).
Ref 536527Emerging drugs for postoperative ileus. Expert Opin Emerg Drugs. 2007 Nov;12(4):619-26.
Ref 536527Emerging drugs for postoperative ileus. Expert Opin Emerg Drugs. 2007 Nov;12(4):619-26.

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