Drug Information

Drug General Information
Drug ID
D00JQE
Former ID
DIB009662
Drug Name
BAY-60-5521
Synonyms
CETP inhibitors (dyslipidemia), Bayer; Cholesteryl ester transfer protein inhibitors (dyslipidemia), Bayer
Indication Arteriosclerosis [ICD9: 440; ICD10:I70] Phase 1 [549303]
Company
Bayer AG
Structure
Download
2D MOL

3D MOL
Canonical SMILES
c1c(ccc(c1)[C@@H](c1c(nc2c(c1C1CCCCC1)[C@H](CC(C2)(C)C)<br />O)C1CCCC1)F)C(F)(F)F
Target and Pathway
Target(s) Cholesteryl ester transfer protein Target Info Inhibitor [531600]
PANTHER Pathway CCKR signaling map ST
Reactome LDL-mediated lipid transport
HDL-mediated lipid transport
WikiPathways Statin Pathway
Lipid digestion, mobilization, and transport
References
Ref 549303Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034993)
Ref 531600Single dose pharmacokinetics, pharmacodynamics, tolerability and safety of BAY 60-5521, a potent inhibitor of cholesteryl ester transfer protein. Br J Clin Pharmacol. 2012 Feb;73(2):210-8.

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