Drug Information

Drug General Information
Drug ID
D00LGA
Former ID
DIB004301
Drug Name
NN-8226
Synonyms
NNC-109-0012; IL-20 monoclonal antibody (inflammation), Novo Nordisk; Anti-IL20 (inflammation), ZymoGenetics/Novo Nordisk; Anti-IL20mAb (RA), ZymoGenetics/Novo Nordisk; Anti-interleukin-20 (rheumatoid arthritis), ZymoGenetics/Novo Nordisk
Drug Type
Antibody
Indication Psoriasis [ICD9: 696; ICD10:L40] Phase 2 [524692]
Company
ZymoGenetics Inc
Target and Pathway
Target(s) Interleukin-20 Target Info [551834]
KEGG Pathway Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
References
Ref 524692ClinicalTrials.gov (NCT02097264) A Trial Investigating the Mechanism of Action of NNC0109-0012 (Anti-IL-20 mAb) Through Synovial Biopsies in Subjects With Rheumatoid Arthritis and an Inadequate Response to Methotrexate. U.S. National Institutes of Health.
Ref 551834Handbook of Therapeutic Antibodies. 2014. 1. Page(995).

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