Drug General Information
Drug ID
D00LPZ
Former ID
DIB014223
Drug Name
Vapill
Synonyms
Vapill; BTT-2026; BTT-2027; BTT-2052; SzV-1287; SzV-1928; SzV-2007; SzV-626; VAP-1 SSAO inhibitor, BioTie; VAP-1 SSAO inhibitors (inflammatory diseases); VAP-1 SSAO inhibitors (inflammatory diseases), BioTie/Seikagaku
Indication Diabetes [ICD9: 253.5, 588.1; ICD10:E23.2, N25.1] Investigative [543706]
Company
BioTie Therapies Corp
Structure
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2D MOL

3D MOL

Canonical SMILES
c1(CC/C=N/O)oc(c(n1)c1ccccc1)c1ccccc1
Target and Pathway
Target(s) Membrane copper amine oxidase Target Info Inhibitor [543706]
BioCyc Pathway Phenylethylamine degradation I
Spermine and spermidine degradation I
KEGG Pathway Glycine, serine and threonine metabolism
Tyrosine metabolism
Phenylalanine metabolism
beta-Alanine metabolism
Metabolic pathways
PANTHER Pathway Phenylethylamine degradation
PathWhiz Pathway Beta-Alanine Metabolism
References
Ref 543706(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2767).
Ref 543706(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2767).

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