Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D00NUB
|
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| Former ID |
DIB019276
|
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| Drug Name |
compound 17
|
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| Drug Type |
Small molecular drug
|
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| Formula |
C19H15Cl2FO3
|
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| InChI |
InChI=1S/C19H15Cl2FO3/c20-9-3-15-13-2-1-10(22)5-14(13)16(19(15)17(21)4-9)8-12-6-11(23)7-18(24)25-12/h1-5,11-12,16,23H,6-8H2/t11-,12?,16?/m1/s1
|
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| InChIKey |
GRRYPQNGDOCSIL-OPGSHWCFSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Target Info | Inhibitor | [533477] | |
| PANTHER Pathway | Cholesterol biosynthesis | ||||
| PathWhiz Pathway | Steroid Biosynthesis | ||||
| References | |||||
| Ref 533477 | 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 5. 6-(Fluoren-9-yl)- and 6-(fluoren-9-ylidenyl)-3,5-dihydroxyhexanoic acids and their lactone derivatives. J Med Chem. 1986 May;29(5):852-5. | ||||
| Ref 539986 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2974). | ||||
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