Drug General Information
Drug ID	D00OBI
Former ID	DNC005935
Drug Name	4-methyl-2-oxo-2H-chromen-7-yl sulfamate
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527782]
Structure		Download 2D MOL 3D MOL
Formula	C10H9NO5S
Canonical SMILES	CC1=CC(=O)OC2=C1C=CC(=C2)OS(=O)(=O)N
InChI	1S/C10H9NO5S/c1-6-4-10(12)15-9-5-7(2-3-8(6)9)16-17(11,13)14/h2-5H,1H3,(H2,11,13,14)
InChIKey	UFGBGFMPBMEVMI-UHFFFAOYSA-N
PubChem Compound ID	9859866
Target and Pathway
Target(s)	Carbonic anhydrase II	Target Info	Inhibitor	[527782]
KEGG Pathway	Nitrogen metabolism
	Proximal tubule bicarbonate reclamation
	Collecting duct acid secretion
	Gastric acid secretion
	Pancreatic secretion
	Bile secretion
NetPath Pathway	IL4 Signaling Pathway
	EGFR1 Signaling Pathway
Reactome	Erythrocytes take up carbon dioxide and release oxygen
	Erythrocytes take up oxygen and release carbon dioxide
	Reversible hydration of carbon dioxide
WikiPathways	Reversible Hydration of Carbon Dioxide
	Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
	Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
References
Ref 527782	Bioorg Med Chem Lett. 2005 Dec 1;15(23):5192-6. Epub 2005 Oct 3.Carbonic anhydrase inhibitors: inhibition of the human isozymes I, II, VA, and IX with a library of substituted difluoromethanesulfonamides.
Ref 527782	Bioorg Med Chem Lett. 2005 Dec 1;15(23):5192-6. Epub 2005 Oct 3.Carbonic anhydrase inhibitors: inhibition of the human isozymes I, II, VA, and IX with a library of substituted difluoromethanesulfonamides.

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