TTD | Drug: D00ODL

Drug General Information
Drug ID	D00ODL
Former ID	DIB020070
Drug Name	IQM-97423
Synonyms	IQM-97,423
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[543266]
Structure		Download 2D MOL
Formula	C31H38N6O4
InChI	InChI=1S/C31H38N6O4/c1-31(2,3)35-29(40)34-25(16-21-18-32-23-13-8-7-12-22(21)23)28(39)33-24-14-9-15-36-26(24)17-27(38)37(30(36)41)19-20-10-5-4-6-11-20/h4-8,10-13,18,24-26,32H,9,14-17,19H2,1-3H3,(H,33,39)(H2,34,35,40)/t24-,25+,26+/m1/s1
InChIKey	JQMXXJDAKTTXOB-ZNZIZOMTSA-N
PubChem Compound ID	11757476
PubChem Substance ID	16865256, 23838882, 42799501, 76055132, 135650413, 163322898
Target and Pathway
Target(s)	Cholecystokinin receptor type A	Target Info	Antagonist	[527185]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Insulin secretion
	Pancreatic secretion
Reactome	Peptide ligand-binding receptors
Reactome	G alpha (q) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 543266	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 876).
Ref 527185	Pharmacological study of IQM-97,423, a potent and selective CCK1 receptor antagonist with protective effect in experimental acute pancreatitis. Pharmacology. 2004 Oct;72(2):68-76.

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Drug Information