Drug Information

Drug General Information
Drug ID
D00QOL
Former ID
DNC007077
Drug Name
3-benzyl-1-cyclohexylpyrrolidin-2-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528391]
Structure
Download
2D MOL

3D MOL
Formula
C17H23NO
Canonical SMILES
C1CCC(CC1)N2CCC(C2=O)CC3=CC=CC=C3
InChI
1S/C17H23NO/c19-17-15(13-14-7-3-1-4-8-14)11-12-18(17)16-9-5-2-6-10-16/h1,3-4,7-8,15-16H,2,5-6,9-13H2
InChIKey
DGGDICYTCJZLPW-UHFFFAOYSA-N
PubChem Compound ID
11673314
Target and Pathway
Target(s) Corticosteroid 11-beta-dehydrogenase, isozyme 1 Target Info Inhibitor [528391]
KEGG Pathway Steroid hormone biosynthesis
Metabolism of xenobiotics by cytochrome P450
Metabolic pathways
Chemical carcinogenesis
NetPath Pathway IL1 Signaling Pathway
FSH Signaling Pathway
PathWhiz Pathway Steroidogenesis
Reactome Glucocorticoid biosynthesis
WikiPathways Prostaglandin Synthesis and Regulation
Metabolism of steroid hormones and vitamin D
Glucocorticoid & Mineralcorticoid Metabolism
References
Ref 528391Bioorg Med Chem Lett. 2006 Nov 1;16(21):5555-60. Epub 2006 Aug 23.Discovery of orally active butyrolactam 11beta-HSD1 inhibitors.
Ref 528391Bioorg Med Chem Lett. 2006 Nov 1;16(21):5555-60. Epub 2006 Aug 23.Discovery of orally active butyrolactam 11beta-HSD1 inhibitors.

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