Drug Information
Drug General Information | |||||
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Drug ID |
D00SPK
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Former ID |
DIB004276
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Drug Name |
E-4021
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Drug Type |
Small molecular drug
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Indication | Cardiovascular disorder [ICD10:I00-I99] | Discontinued in Phase 2 | [545643] | ||
Company |
Eisai Co Ltd
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Structure |
Download2D MOL |
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Formula |
C22H20ClN4NaO4
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Canonical SMILES |
c12c(nc(nc1ccc(c2)Cl)N1CCC(CC1)C(=O)[O-])NCc1cc2c(cc1)O<br />CO2.[Na+]
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CAS Number |
CAS 150452-18-9
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | CGMP-specific 3',5'-cyclic phosphodiesterase | Target Info | Inhibitor | [525427] | |
KEGG Pathway | Purine metabolism | ||||
cGMP-PKG signaling pathway | |||||
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
Reactome | cGMP effects | ||||
References |
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