Drug Information

Drug General Information
Drug ID
D00UFZ
Former ID
DNCL001600
Drug Name
AMG 745
Indication Muscular atrophy [ICD9: 728.2; ICD10:M62.5] Phase 2 [522779]
Company
Amgen
Target and Pathway
Target(s) Growth/differentiation factor 8 Target Info Antagonist [544190]
PANTHER Pathway TGF-beta signaling pathway
WikiPathways Hypertrophy Model
References
Ref 522779ClinicalTrials.gov (NCT00975104) AMG 745 in Subjects With Age-associated Muscle Loss. U.S. National Institutes of Health.
Ref 544190The role of myostatin in muscle wasting: an overview. J Cachexia Sarcopenia Muscle. 2011 September; 2(3): 143-151.

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