Drug General Information
Drug ID	D00UPU
Former ID	DIB000444
Drug Name	RPR-107836
Synonyms	IDDB8561
Indication	Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42]		Investigative	[543961]
Company	Rhone-Poulenc Rorer Inc
Structure		Download 2D MOL 3D MOL
Canonical SMILES	N1([C@H](SC[C@H]1C(=O)OC(C)(C)C)c1c(F)cccc1)C(=O)CNC(=O<br />)Nc1cc([C@@H](C(=O)O)OC)ccc1
Target and Pathway
Target(s)	Gastrin/cholecystokinin type B receptor	Target Info	Modulator	[543961]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Gastric acid secretion
PANTHER Pathway	CCKR signaling map ST
PathWhiz Pathway	Gastric Acid Production
Reactome	Peptide ligand-binding receptors
	G alpha (q) signalling events
	Gastrin-CREB signalling pathway via PKC and MAPK
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Secretion of Hydrochloric Acid in Parietal Cells
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 543961	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 77).
Ref 543961	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 77).

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