Drug Information

Drug General Information
Drug ID
D00XKB
Former ID
DIB018039
Drug Name
AZ-4217
Synonyms
AZ4217; AZ 4217
Drug Type
Small molecular drug
Indication Rheumatoid arthritis [ICD9: 710-719, 714; ICD10:M05-M06] Clinical trial [532395]
Structure
Download
2D MOL
Formula
C30H25FN4O
InChI
InChI=1S/C30H25FN4O/c1-4-8-20-14-22(17-33-16-20)21-9-6-10-23(15-21)30(24-13-19(3)29(36)35(5-2)18-24)25-11-7-12-26(31)27(25)28(32)34-30/h6-7,9-18H,5H2,1-3H3,(H2,32,34)/t30-/m0/s1
InChIKey
TUGLMYZSOPKJOA-PMERELPUSA-N
PubChem Compound ID
57406537
PubChem Substance ID
136952263, 163323567, 163342112, 178103521, 235298758
Target and Pathway
Target(s) Beta-secretase Target Info Inhibitor [532395]
References
Ref 532395AZ-4217: a high potency BACE inhibitor displaying acute central efficacy in different in vivo models and reduced amyloid deposition in Tg2576 mice. J Neurosci. 2013 Jun 12;33(24):10075-84.
Ref 532395AZ-4217: a high potency BACE inhibitor displaying acute central efficacy in different in vivo models and reduced amyloid deposition in Tg2576 mice. J Neurosci. 2013 Jun 12;33(24):10075-84.

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