Drug Information

Drug General Information
Drug ID
D00YZD
Former ID
DNCL002987
Drug Name
Dolutegravir
Synonyms
S/GSK1349572; DTG
Drug Type
Small molecular drug
Indication Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] Approved [532651], [542387]
Company
GlaxoSmithKline
Structure
Download
2D MOL

3D MOL
Formula
C20H19F2N3O5
InChI
InChI=1S/C20H19F2N3O5/c1-10-4-5-30-15-9-24-8-13(17(26)18(27)16(24)20(29)25(10)15)19(28)23-7-11-2-3-12(21)6-14(11)22/h2-3,6,8,10,15,27H,4-5,7,9H2,1H3,(H,23,28)/t10-,15+/m1/s1
InChIKey
RHWKPHLQXYSBKR-BMIGLBTASA-N
PubChem Compound ID
54726191
PubChem Substance ID
96100998, 123055423, 124361075, 124361082, 124361088, 135268073, 135273443, 135626786, 136340316, 136349541, 136367672, 136920429, 144115916, 152258477, 160647312, 160693271, 162011364, 162038052, 162202774, 163677014, 164043525, 164193963, 164347381, 170484068, 170484069, 170484070, 170503405, 174007466, 174525979, 175427161, 178103937, 184812380, 189622844, 198935766, 198993556, 223382143, 223705174, 226460906, 242590891, 248390482, 250184664, 252110159, 252224388, 252451605
SuperDrug ATC ID
J05AX12
Drug Resistance Mutation (DRM)
DRM DRM Info
Target and Pathway
Target(s) HIV integrase Target Info Modulator [532651]
References
Ref 5326512013 FDA drug approvals. Nat Rev Drug Discov. 2014 Feb;13(2):85-9.
Ref 542387(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7365).
Ref 5326512013 FDA drug approvals. Nat Rev Drug Discov. 2014 Feb;13(2):85-9.

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