Drug Information

Drug General Information
Drug ID
D01ADL
Former ID
DIB013019
Drug Name
Roledumab
Synonyms
DMATRIA; LFB-R593; R-297; R-593; Anti-D human monoclonal antibody, Laboratoire Francais du Fractionnement et des Biotechnologies; R297 antibody (hematological disease), LFB; R297 antibody (hematological disease), Laboratoire Francais du Fractionnement et des Biotechnologies; Anti-RhD antibody (hematological disease), LFB; Anti-rhesus D mAB (hematological disease), LFB
Drug Type
Antibody
Indication Anemia [ICD9: 280-285; ICD10:D50-D64] Phase 2/3 [524990]
Company
LFB Biotechnologies
Target and Pathway
Target(s) Blood group Rh(D) polypeptide Target Info [531898]
References
Ref 524990ClinicalTrials.gov (NCT02287896) Pharmacokinetics and Safety of Roledumab, in RhD-negative Pregnant Women Carrying an RhD-positive Foetus. U.S. National Institutes of Health.
Ref 531898Pharmacokinetics and safety of roledumab, a novel human recombinant monoclonal anti-RhD antibody with an optimized Fc for improved engagement of FCgammaRIII, in healthy volunteers. Vox Sang. 2012 Oct;103(3):213-22.

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