Drug Information

Drug General Information
Drug ID
D01AFG
Former ID
DNCL002642
Drug Name
RG7414
Indication Non-small-cell lung cancer; Metastatic colorectal cancer [ICD9: 140-199, 140-229, 153, 154, 162, 204.0, 210-229; ICD10:C18-C21, C33, C33-C34, C34, C91.0, D10-D36, D3A] Discontinued in Phase 2 [548970]
Company
Genentech
Target and Pathway
Target(s) EGF-like domain-containing protein 7 Target Info Modulator [544335]
References
Ref 548970Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800030998)
Ref 544335Anti-EGFL7 antibodies enhance stress-induced endothelial cell death and anti-VEGF efficacy. J Clin Invest. 2013 September 3; 123(9): 3997-4009.

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