Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D01AGR
|
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| Former ID |
DNC008885
|
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| Drug Name |
1-[5-(4-Chlorophenyl)-2-furoyl]piperazine
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C15H15ClN2O2
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | PN3 Na+ channel | Target Info | Inhibitor | [1] | |
| Voltage-gated sodium channel subunit alpha Nav1.8 | Target Info | Inhibitor | [1] | ||
| Sodium channel protein type 5 subunit alpha | Target Info | Inhibitor | [1] | ||
| KEGG Pathway | Adrenergic signaling in cardiomyocytes | ||||
| PathWhiz Pathway | Muscle/Heart Contraction | ||||
| Reactome | Interaction between L1 and AnkyrinsR-HSA-445095:Interaction between L1 and Ankyrins | ||||
| WikiPathways | SIDS Susceptibility Pathways | ||||
| Cardiac Progenitor Differentiation | |||||
| References | |||||
| REF 1 | Bioorg Med Chem. 2008 Jun 15;16(12):6379-86. Epub 2008 May 6.Discovery of potent furan piperazine sodium channel blockers for treatment of neuropathic pain. | ||||
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