Drug Information

Drug General Information
Drug ID
D01BEX
Former ID
DIB003625
Drug Name
PRS-060
Synonyms
IL-4 alpha receptor inhibitor (Anticalin, asthma), Pieris; IL-4R alpha inhibitor (Anticalin, asthma), Pieris
Indication Asthma [ICD10:J45] Investigative [543460]
Company
Pieris AG
Target and Pathway
Target(s) Interleukin-4 receptor alpha chain Target Info Inhibitor [543460]
KEGG Pathway Cytokine-cytokine receptor interaction
PI3K-Akt signaling pathway
Jak-STAT signaling pathway
Hematopoietic cell lineage
Inflammatory bowel disease (IBD)
NetPath Pathway IL2 Signaling Pathway
IL4 Signaling Pathway
EGFR1 Signaling Pathway
PANTHER Pathway Interleukin signaling pathway
Pathway Interaction Database p73 transcription factor network
IL4-mediated signaling events
WikiPathways Inflammatory Response Pathway
IL-4 Signaling Pathway
References
Ref 543460(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1697).
Ref 543460(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1697).

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