TTD | Drug: D01DOY

Drug General Information
Drug ID	D01DOY
Former ID	DIB002665
Drug Name	GR-127607
Indication	Migraine [ICD9: 346; ICD10:G43]		Discontinued in Phase 1	[545504]
Company	Glaxo Group Research Ltd
Target and Pathway
Target(s)	5-hydroxytryptamine 1A receptor	Target Info	Agonist	[545505]
KEGG Pathway	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PANTHER Pathway	5HT1 type receptor mediated signaling pathway
Reactome	Serotonin receptors
Reactome	G alpha (i) signalling events
WikiPathways	Serotonin HTR1 Group and FOS Pathway
	SIDS Susceptibility Pathways
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 545504	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003531)
Ref 545505	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003531)

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Drug Information