Drug Information

Drug General Information
Drug ID
D01DSP
Former ID
DAP001160
Drug Name
Cephapirin
Synonyms
CEPR; Cefa; Cefadyl; Cefapirin; Cefapirina; Cefapirine; Cefapirinum; Cefaprin; Cephapirine; Metricure; CEPHAPIRIN SODIUM; Cefaprinsodium; Cephapirin Monosodium Salt; ANTIBIOTIC BL-P1322; BL-P 1322; Cefa-ak; Cefadyl (TN); Cefapirin (BAN); Cefapirin [INN:BAN]; Cefapirina [INN-Spanish]; Cefapirine [INN-French]; Cefapirinum [INN-Latin]; Metricure (TN); (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(4-pyridylthio)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carbonsaeure; (6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-pyridin-4-ylsulfanylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; (6R,7R)-3-[(acetyloxy)methyl]-8-oxo-7-{[(pyridin-4-ylthio)acetyl]amino}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; (6R,7R)-3-acetoxymethyl-7-[(pyridin-4-ylsulfanyl)acetamido]-3,4-didehydrocepham-4-carboxylic acid; 3-(Hydroxymethyl)-8-oxo-7-(2-(4-pyridylthio)acetamidol-5-thia-1-azabicyclo(4.2.0)oct-2-en-2carbonsaeure acetat; 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-(hydroxymethyl)-8-oxo-7-(2-(4-pyridylthio)acetamido)-, acetate (ester); 7-(2-(4-Pyridylthio)acetamido)cephalosporanic acid
Drug Type
Small molecular drug
Indication Sepsis [ICD9: 995.91; ICD10:A40, A41] Approved [538207], [551871]
Therapeutic Class
Antibiotics
Structure
Download
2D MOL

3D MOL
Formula
C17H17N3O6S2
Canonical SMILES
CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)CSC3=CC=NC=C3)SC1)C(=O)O
InChI
1S/C17H17N3O6S2/c1-9(21)26-6-10-7-28-16-13(15(23)20(16)14(10)17(24)25)19-12(22)8-27-11-2-4-18-5-3-11/h2-5,13,16H,6-8H2,1H3,(H,19,22)(H,24,25)/t13-,16-/m1/s1
InChIKey
UQLLWWBDSUHNEB-CZUORRHYSA-N
CAS Number
CAS 21593-23-7
PubChem Compound ID
30699
PubChem Substance ID
9113, 602885, 8171717, 11335217, 11360456, 11362966, 11365528, 11368090, 11371285, 11373879, 11376252, 11461428, 11466879, 11467999, 11483822, 11486518, 11487919, 11490149, 11492085, 11493926, 15452100, 34672911, 46505227, 47440073, 47515148, 47588824, 47885243, 48184822, 48415744, 50050995, 51091940, 57310975, 74511317, 87323458, 103590583, 104133804, 104308908, 117600530, 124766406, 129405974, 134223575, 134338405, 134995684, 137003415, 140396434, 152035918, 160849694, 160964473, 162497207, 175266904
SuperDrug ATC ID
J01DB08
SuperDrug CAS ID
cas=021593237
Target and Pathway
Target(s) DNA Target Info Binder [537909]
References
Ref 538207FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 062720.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 537909The formation of functional penicillin-binding proteins. J Biol Chem. 1975 Aug 25;250(16):6578-85.

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