Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D01GUS
|
||||
Former ID |
DAP000960
|
||||
Drug Name |
Udenafil
|
||||
Synonyms |
Zydena; DA 8159; DA-8159; Zydena (TN); 3-(1-methyl-7-oxo-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-[2-(1-methylpyrrolidin-2-yl)ethyl]-4-propoxybenzenesulfonamide; 5-(2-Propyloxy-5-(1-methyl-2-pyrollidinylethylamidosulfonyl)phenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo(4,3-d)pyrimidine-7-one
|
||||
Drug Type |
Small molecular drug
|
||||
Indication | Erectile dysfunction [ICD9: 302.72, 607.84; ICD10:F52.2, N48.4] | Approved | [536361] | ||
Therapeutic Class |
Vasodilator Agents
|
||||
Company |
Dong-A Pharmaceutical
|
||||
Structure |
Download2D MOL |
||||
Formula |
C25H36N6O4S
|
||||
Canonical SMILES |
CCCC1=NN(C2=C1NC(=NC2=O)C3=C(C=CC(=C3)S(=O)(=O)NCCC4CCC<br />N4C)OCCC)C
|
||||
InChI |
1S/C25H36N6O4S/c1-5-8-20-22-23(31(4)29-20)25(32)28-24(27-22)19-16-18(10-11-21(19)35-15-6-2)36(33,34)26-13-12-17-9-7-14-30(17)3/h10-11,16-17,26H,5-9,12-15H2,1-4H3,(H,27,28,32)
|
||||
InChIKey |
IYFNEFQTYQPVOC-UHFFFAOYSA-N
|
||||
CAS Number |
CAS 268203-93-6
|
||||
PubChem Compound ID | |||||
PubChem Substance ID |
12015432, 15181651, 16896098, 17194940, 43529893, 50430522, 57371963, 99443240, 99452560, 104178316, 114788102, 134224591, 134338234, 134340602, 135271929, 135626747, 137082780, 137237692, 138091955, 138937364, 141714788, 152041640, 160687015, 160967855, 163108842, 164235286, 164766037, 176251591, 196411563, 210275732, 210281393, 223922924, 226492530, 246737278
|
||||
Target and Pathway | |||||
Target(s) | CGMP-specific 3',5'-cyclic phosphodiesterase | Target Info | Inhibitor | [537372] | |
KEGG Pathway | Purine metabolism | ||||
cGMP-PKG signaling pathway | |||||
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
Reactome | cGMP effects | ||||
References |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.