Drug Information

Drug General Information
Drug ID
D01HAZ
Former ID
DNC007836
Drug Name
3-(dibutylamino)-1-(4-hexylphenyl)propan-1-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529081]
Structure
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2D MOL

3D MOL
Formula
C23H39NO
Canonical SMILES
CCCCCCC1=CC=C(C=C1)C(=O)CCN(CCCC)CCCC
InChI
1S/C23H39NO/c1-4-7-10-11-12-21-13-15-22(16-14-21)23(25)17-20-24(18-8-5-2)19-9-6-3/h13-16H,4-12,17-20H2,1-3H3
InChIKey
UMFRWWULZNWTFF-UHFFFAOYSA-N
PubChem Compound ID
23635364
Target and Pathway
Target(s) Thyroid hormone receptor alpha Target Info Inhibitor [529081]
Thyroid hormone receptor beta-1 Target Info Inhibitor [529081]
KEGG Pathway Neuroactive ligand-receptor interaction
Thyroid hormone signaling pathwayhsa04080:Neuroactive ligand-receptor interaction
Thyroid hormone signaling pathway
Pathway Interaction Database RXR and RAR heterodimerization with other nuclear receptorrxr_vdr_pathway:RXR and RAR heterodimerization with other nuclear receptor
Reactome Nuclear Receptor transcription pathwayR-HSA-383280:Nuclear Receptor transcription pathway
WikiPathways Endochondral Ossification
Nuclear ReceptorsWP706:SIDS Susceptibility Pathways
Hematopoietic Stem Cell Differentiation
Nuclear Receptors
References
Ref 529081J Med Chem. 2007 Nov 1;50(22):5269-80. Epub 2007 Oct 5.Inhibitors of the interaction of a thyroid hormone receptor and coactivators: preliminary structure-activity relationships.
Ref 529081J Med Chem. 2007 Nov 1;50(22):5269-80. Epub 2007 Oct 5.Inhibitors of the interaction of a thyroid hormone receptor and coactivators: preliminary structure-activity relationships.

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