Drug General Information
Drug ID	D01HXA
Former ID	DNCL001624
Drug Name	AUS-131
Indication	Hot flashes [ICD10:N95.1]		Phase 2	[548914]
Company	Ausio Pharmaceuticals
Structure		Download 2D MOL 3D MOL
Target and Pathway
Target(s)	Estrogen receptor beta	Target Info	Agonist	[527547]
KEGG Pathway	Estrogen signaling pathway
	Prolactin signaling pathway
Pathway Interaction Database	Plasma membrane estrogen receptor signaling
	Validated nuclear estrogen receptor beta network
	Validated nuclear estrogen receptor alpha network
Reactome	Nuclear Receptor transcription pathway
WikiPathways	SIDS Susceptibility Pathways
	Ovarian Infertility Genes
	Integrated Pancreatic Cancer Pathway
	Nuclear Receptors
References
Ref 548914	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800030256)
Ref 527547	S-equol, a potent ligand for estrogen receptor beta, is the exclusive enantiomeric form of the soy isoflavone metabolite produced by human intestinal bacterial flora. Am J Clin Nutr. 2005 May;81(5):1072-9.

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