Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D01KKE
|
||||
| Former ID |
DCL000834
|
||||
| Drug Name |
GW876008
|
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| Synonyms |
GW-876008
|
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| Drug Type |
Small molecular drug
|
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| Indication | Irritable bowel syndrome [ICD9: 564.1, 787.91; ICD10:A09, K58, K59.1] | Discontinued in Phase 2 | [536580] | ||
| Company |
GSK
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C22H24N6O2
|
||||
| Canonical SMILES |
CC1=C(C=CC(=C1)OC)N2CCC3=C2N=C(C=C3N4C=CC(=N4)N5CCNC5=O<br />)C
|
||||
| InChI |
1S/C22H24N6O2/c1-14-12-16(30-3)4-5-18(14)26-9-6-17-19(13-15(2)24-21(17)26)28-10-7-20(25-28)27-11-8-23-22(27)29/h4-5,7,10,12-13H,6,8-9,11H2,1-3H3,(H,23,29)
|
||||
| InChIKey |
JFHJGXQFESYQGY-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Corticotropin releasing factor receptor 1 | Target Info | Antagonist | [536580] | |
| NetPath Pathway | TNFalpha Signaling Pathway | ||||
| PANTHER Pathway | Cortocotropin releasing factor receptor signaling pathway | ||||
| References | |||||
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