Drug Information

Drug General Information
Drug ID
D01LAU
Former ID
DNC008529
Drug Name
5-methoxycarbonylamino-N-acetyltryptamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540341]
Structure
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2D MOL

3D MOL
Formula
C14H17N3O3
InChI
InChI=1S/C14H17N3O3/c1-9(18)15-6-5-10-8-16-13-4-3-11(7-12(10)13)17-14(19)20-2/h3-4,7-8,16H,5-6H2,1-2H3,(H,15,18)(H,17,19)
InChIKey
MPZVHKLZCUEJFO-UHFFFAOYSA-N
PubChem Compound ID
4284525
PubChem Substance ID
6290404, 7978608, 9627826, 11113768, 14750699, 26751952, 29215031, 35542592, 47583802, 48329131, 57356892, 71753364, 79639898, 85787577, 91614382, 103619802, 104110036, 112845218, 123050766, 128631352, 134221808, 134345734, 135698167, 137186245, 142405033, 162022746, 162247320, 162967835, 164761931, 178100406, 184594788, 204371613, 223759866, 230562864, 241181962, 241377516, 249776595
Target and Pathway
Target(s) Melatonin receptor type 1B Target Info Inhibitor [529396]
Melatonin receptor Target Info Inhibitor [529396]
KEGG Pathway Neuroactive ligand-receptor interaction
Circadian entrainmenthsa04080:Neuroactive ligand-receptor interaction
Circadian entrainment
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling eventsR-HSA-373076:Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signalingWP455:GPCRs, Class A Rhodopsin-like
GPCR downstream signaling
References
Ref 540341(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3393).
Ref 529396Bioorg Med Chem. 2008 May 1;16(9):4954-62. Epub 2008 Mar 17.Design and synthesis of benzofuranic derivatives as new ligands at the melatonin-binding site MT3.

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