Drug Information

Drug General Information
Drug ID
D01MJF
Former ID
DNC008379
Drug Name
JWH-404
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529084]
Structure
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2D MOL

3D MOL
Formula
C22H36O
Canonical SMILES
CCCCCCCC(C)(C)C1=CC=C(C=C1)C2CCCC(C2)O
InChI
1S/C22H36O/c1-4-5-6-7-8-16-22(2,3)20-14-12-18(13-15-20)19-10-9-11-21(23)17-19/h12-15,19,21,23H,4-11,16-17H2,1-3H3/t19-,21+/m0/s1
InChIKey
SHSCKELICBAALI-PZJWPPBQSA-N
PubChem Compound ID
44452622
Target and Pathway
Target(s) Cannabinoid receptor 2 Target Info Inhibitor [529084]
Cannabinoid receptor 1 Target Info Inhibitor [529084]
KEGG Pathway Neuroactive ligand-receptor interactionhsa04015:Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling eventsR-HSA-373076:Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signalingWP455:GPCRs, Class A Rhodopsin-like
BDNF signaling pathway
GPCR downstream signaling
GPCRs, Other
References
Ref 529084Bioorg Med Chem. 2008 Jan 1;16(1):322-35. Epub 2007 Sep 22.Synthesis and pharmacology of 1-deoxy analogs of CP-47,497 and CP-55,940.
Ref 529084Bioorg Med Chem. 2008 Jan 1;16(1):322-35. Epub 2007 Sep 22.Synthesis and pharmacology of 1-deoxy analogs of CP-47,497 and CP-55,940.

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